Which antibiotic is contraindicated in large-breed dogs?

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Multiple Choice

Which antibiotic is contraindicated in large-breed dogs?

Explanation:
Fluoroquinolones carry a risk to developing joints. In skeletally immature animals, especially large-breed puppies that are growing rapidly, enrofloxacin can cause irreversible cartilage erosion in weight-bearing joints. Because of this potential for lasting orthopedic damage, enrofloxacin is contraindicated in growing large-breed dogs. Other antibiotics listed do not have the same growth-plate cartilage toxicity risk and are not contraindicated for large-breed puppies on the basis of this safety concern.

Fluoroquinolones carry a risk to developing joints. In skeletally immature animals, especially large-breed puppies that are growing rapidly, enrofloxacin can cause irreversible cartilage erosion in weight-bearing joints. Because of this potential for lasting orthopedic damage, enrofloxacin is contraindicated in growing large-breed dogs. Other antibiotics listed do not have the same growth-plate cartilage toxicity risk and are not contraindicated for large-breed puppies on the basis of this safety concern.

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